2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine

For research use only. Not for therapeutic Use.

  • CAT Number: L032115
  • CAS Number: 681249-56-9
  • Molecular Formula: C6H3F3N4
  • Molecular Weight: 188.11
  • Purity: ≥95%
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2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine(CAT: L032115) is a nitrogen-rich heterocyclic compound valued in pharmaceutical and chemical research for its unique structural and electronic properties. The triazolopyrazine core, combined with a trifluoromethyl group at the 2-position, enhances its metabolic stability, lipophilicity, and potential for biological activity. The trifluoromethyl group, a common pharmacophore, improves bioavailability and target binding due to its electron-withdrawing nature. This compound serves as a versatile scaffold for developing inhibitors, receptor modulators, and other bioactive agents, making it useful in drug discovery programs, particularly those focused on central nervous system and oncology targets. Its structure enables modifications that can optimize potency and selectivity for specific biochemical pathways.


Catalog Number L032115
CAS Number 681249-56-9
Molecular Formula C6H3F3N4
Purity ≥95%
IUPAC Name 2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine
InChI InChI=1S/C6H3F3N4/c7-6(8,9)5-11-4-3-10-1-2-13(4)12-5/h1-3H
InChIKey PODZNIVAQJSKBB-UHFFFAOYSA-N

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