20β-Dihydrocortisol(CAT: R060042) is a natural metabolite of cortisol, a glucocorticoid hormone involved in regulating various physiological processes, including the body’s response to stress, inflammation, and immune function. This specific cortisol derivative is of interest in endocrinology and pharmacology for studying cortisol metabolism and its related pathways. By examining 20β-Dihydrocortisol, researchers can gain insights into cortisol’s degradation, the functioning of the adrenal gland, and disorders like Cushing’s syndrome and adrenal insufficiency. It is also used in studies related to glucocorticoid receptor interactions and its broader impact on metabolic and inflammatory processes in the body.
| Catalog Number | R060042 |
| CAS Number | 116-58-5 |
| Synonyms | 11β,17,20β,21-Tetrahydroxy-pregn-4-en-3-one; 11β,17,20β,21-Tetrahydroxy-4-pregnen-3-one; 11β,17α,20β,21-Tetrahydroxy-pregn-4-en-3-one; 17-(1,2-Dihydroxyethyl)androsten-3-one-11,17-diol; 20β-Hydroxycortisol; 4-Pregene-11β,17α,20β,21-tetrol-3-one; 4-Pr |
| Molecular Formula | C21H32O5 |
| Purity | ≥95% |
| Storage | Store at -80C |
| IUPAC Name | (8S,9S,10R,11S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one |
| InChI | InChI=1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-18,22,24-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,17+,18+,19-,20-,21-/m0/s1 |
| InChIKey | AWWCEQOCFFQUKS-LCGKLAOVSA-N |
| SMILES | CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(CO)O)O)C)O |
