20β-Dihydrocortisone

• CAT Number: R060085
• CAS Number: 116-59-6
• Molecular Formula: C21H30O5
• Molecular Weight: 362.47
• Purity: ≥95%
• Synonyms: 17,20β,21-Trihydroxy-pregn-4-ene-3,11-dione; 17,20β,21-Trihydroxypregn-4-ene-3,11-dione; 17α,20β,21-Trihydroxy-4-pregnene-3,11-dione; 20β-Hydroxycortisone; Pregn-4-en-17α,20β,21-triol-3,11-dione; Pregn-4-ene-17α,20β,21-triol-3,11-dione; Reichstein’s
• Storage: -20°C
• IUPAC Name: (8S,9S,10R,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
• InChI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,17-18,22,25-26H,3-8,10-11H2,1-2H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1
• InChIKey: XBIDABJJGYNJTK-GNIMZFFESA-N
• SMILES: CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4(C(CO)O)O)C

20β-Dihydrocortisone(CAT: R060085) is a metabolite of cortisone, a glucocorticoid hormone involved in the regulation of inflammation, immune responses, and metabolic processes. This metabolite is produced during the metabolism of cortisone and is commonly studied to better understand glucocorticoid activity, as well as the broader implications of steroid metabolism in conditions like adrenal disorders, including Addison’s disease and Cushing’s syndrome. Research into 20β-Dihydrocortisone provides insights into the pharmacokinetics and pharmacodynamics of corticosteroids, aiding in the development of therapeutic strategies for managing inflammation, immune modulation, and stress responses.