(20S)-Protopanaxatriol

• CAT Number: I003234
• CAS Number: 34080-08-5
• Molecular Formula: C30H52O4
• Molecular Weight: 476.73
• Purity: ≥95%
• Solubility: DMSO: ≥ 47 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol
• InChI: InChI=1S/C30H52O4/c1-18(2)10-9-13-30(8,34)19-11-15-28(6)24(19)20(31)16-22-27(5)14-12-23(33)26(3,4)25(27)21(32)17-29(22,28)7/h10,19-25,31-34H,9,11-17H2,1-8H3/t19-,20+,21-,22+,23-,24-,25-,27+,28+,29+,30-/m0/s1
• InChIKey: SHCBCKBYTHZQGZ-CJPZEJHVSA-N
• SMILES: CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)O)C)O)C)O)C

(20S)-Protopanaxatriol (Cat.No: I003234), also known as ginsenoside Rh1, is a triterpene saponin derived from ginseng. It has been studied for its potential pharmacological effects, including anti-inflammatory, neuroprotective, and antitumor activities. Additionally, it has been shown to have cardioprotective effects, particularly in the treatment of heart failure.

Reference

[1]. Han KL, et al. Ginsenoside 20S-protopanaxatriol (PPT) activates peroxisome proliferator-activated receptor gamma (PPARgamma) in 3T3-L1 adipocytes. Biol Pharm Bull. 2006 Jan;29(1):110-3.
[2]. Leung KW, et al. Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells. Br J Pharmacol. 2009 Feb;156(4):626-37.