21-Chloro-17α-[(2-furanylcarbonxyl)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dioneMometasone

• CAT Number: R040027
• CAS Number: 83881-09-8
• Molecular Formula: C₂₇H₂₉ClO₆
• Molecular Weight: 484.97
• Purity: ≥95%
• Synonyms: (9β,11β,16α)-21-Chloro-9,11-epoxy-17-[(2-furanylcarbonyl)oxy]-16-methylpregna-1,4-diene-3,20-dione; Mometasone Furoate Impurity D
• Storage: Desiccate at -20°C
• IUPAC Name: [(1S,2S,10S,11S,13R,14R,15S,17S)-14-(2-chloroacetyl)-2,13,15-trimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-14-yl] furan-2-carboxylate
• InChI: InChI=1S/C27H29ClO6/c1-15-11-19-18-7-6-16-12-17(29)8-9-24(16,2)27(18)22(33-27)13-25(19,3)26(15,21(30)14-28)34-23(31)20-5-4-10-32-20/h4-5,8-10,12,15,18-19,22H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,22+,24+,25+,26+,27-/m1/s1
• InChIKey: PGAGVJAYRDPYKY-QVWMRSGNSA-N
• SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C35C(O5)CC2(C1(C(=O)CCl)OC(=O)C6=CC=CO6)C)C

Mometasone, specifically 21-Chloro-17α-[(2-furanylcarbonyl)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione（Cat No.:R040027）, is a potent synthetic corticosteroid used in various medical treatments. It exhibits strong anti-inflammatory, antipruritic, and vasoconstrictive properties, making it effective in treating conditions like allergic rhinitis, asthma, and dermatological disorders. Mometasone works by inhibiting the release of inflammatory mediators and reducing immune response. Its topical formulations, such as creams and nasal sprays, provide targeted relief with minimal systemic absorption, enhancing safety and efficacy. Its versatile therapeutic applications make mometasone a crucial agent in managing inflammation-related conditions.