21-Dehydro Prednisolone

• CAT Number: R057699
• CAS Number: 22420-16-2
• Molecular Formula: C21H26O5
• Molecular Weight: 358.43
• Purity: ≥95%
• Synonyms: (11β)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-al; ?11β,17-Dihydroxy-3,20-dioxopregna-1,4-dien-21-al; 21-Dehydroprednisolone
• Storage: Store at +4 ℃
• IUPAC Name: 2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoacetaldehyde
• InChI: InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,11,14-16,18,24,26H,3-4,6,8,10H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChIKey: OKNNTPJBKBRSIB-VWUMJDOOSA-N
• SMILES: CC12CC(C3C(C1CCC2(C(=O)C=O)O)CCC4=CC(=O)C=CC34C)O

21-Dehydro prednisolone (Cat No.: R057699) is a derivative of prednisolone, a synthetic corticosteroid used to suppress inflammation and modulate immune responses. By removing a hydrogen atom at the 21st position, 21-dehydro prednisolone exhibits slightly altered pharmacological properties compared to its parent compound. This modification can affect its potency, metabolic stability, and receptor affinity. Such derivatives are studied to improve therapeutic profiles, reduce side effects, and enhance drug efficacy for treating a range of inflammatory and autoimmune conditions.