For research use only. Not for therapeutic Use.
Selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells <em>in vitro</em>. IC<sub>50</sub> values are 0.89 and 12.6 <span class=/’symbol/’>μ</span>M for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.
| Catalog Number | I010511 |
| CAS Number | 1009555-55-8 |
| Synonyms | 2-[[3-(2,3-Dichlorophenoxy)propyl]amino]ethanol hydrochloride |
| Molecular Formula | C11H16Cl3NO2 |
| Purity | ≥95% |
| IUPAC Name | 2-[3-(2,3-dichlorophenoxy)propylamino]ethanol;hydrochloride |
| InChI | InChI=1S/C11H15Cl2NO2.ClH/c12-9-3-1-4-10(11(9)13)16-8-2-5-14-6-7-15;/h1,3-4,14-15H,2,5-8H2;1H |
| InChIKey | GFCJFYSIPRIHKT-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)Cl)Cl)OCCCNCCO.Cl |
