For research use only. Not for therapeutic Use.
2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D sodium salt can induce < b>apoptosis. 2,4-D sodium salt inhibits DNA and protein synthesis, thereby preventing normal plant growth and development[1][2][3].
2, 4-D sodium salt (25-200 μM, 72 h) inhibits the cell viability of A549 and WI38 with IC50 values of 126 ± 2.25µM and 115 ± 4.39µM, respectively. By influencing cell cycle, apoptosis was induced[2].
2,4-D sodium salt (100 or 200 mg/kg, gavage for 30 days) has toxic effects on the reproductive system of male rats[3].
| Catalog Number | I015339 |
| CAS Number | 2702-72-9 |
| Synonyms | sodium;2-(2,4-dichlorophenoxy)acetate |
| Molecular Formula | C8H5Cl2NaO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C8H6Cl2O3.Na/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;/h1-3H,4H2,(H,11,12);/q;+1/p-1 |
| InChIKey | RFOHRSIAXQACDB-UHFFFAOYSA-M |
| SMILES | C1=CC(=C(C=C1Cl)Cl)OCC(=O)[O-].[Na+] |
| Reference | [1]. Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57(2):302-10. [2]. Ganguli A, et al. 2, 4-Dichlorophenoxyacetic acid induced toxicity in lung cells by disruption of the tubulin-microtubule network. Toxicology Research, 2014, 3(2): 118-130. [3]. Marouani N, et al. Effects of oral administration of 2,4-dichlorophenoxyacetic acid (2,4-D) on reproductive parameters in male Wistar rats. Environ Sci Pollut Res Int. 2017 Jan;24(1):519-526. |
