2,4-Difluoro-3-(hydroxymethyl)phenylboronic acid

• CAT Number: L024141
• CAS Number: 1352813-46-7
• Molecular Formula: C7H7BF2O3
• Molecular Weight: 187.94
• Purity: ≥95%
• IUPAC Name: [2,4-difluoro-3-(hydroxymethyl)phenyl]boronic acid
• InChI: InChI=1S/C7H7BF2O3/c9-6-2-1-5(8(12)13)7(10)4(6)3-11/h1-2,11-13H,3H2
• InChIKey: AOTLVFMQQQBEHC-UHFFFAOYSA-N
• SMILES: B(C1=C(C(=C(C=C1)F)CO)F)(O)O

2,4-Difluoro-3-(hydroxymethyl)phenylboronic acid is a boronic acid derivative featuring hydroxymethyl and difluoro substituents on a phenyl ring. This compound is significant in organic synthesis, particularly in cross-coupling reactions, such as Suzuki-Miyaura coupling, where it acts as a versatile building block for forming carbon-carbon bonds. The hydroxymethyl group enhances its solubility and reactivity, while the difluoro substituents influence its electronic properties. Its unique structure makes it valuable for developing pharmaceuticals and advanced materials in medicinal chemistry.