25-Hydroxyvitamin D3 3-Hemisuccinate

• CAT Number: R020401
• CAS Number: 69511-19-9
• Molecular Formula: C31H48O5
• Molecular Weight: 500.72
• Purity: ≥95%
• Synonyms: (3β,5Z,7E)- 3-(Hydrogen Butanedioate)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-Hydroxycholecalciferol-3-hemisuccinate; Calcidiol 3-Hemisuccinate
• Storage: -20°C
• IUPAC Name: 4-[(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexyl]oxy-4-oxobutanoic acid
• InChI: InChI=1S/C31H48O5/c1-21-10-13-25(36-29(34)17-16-28(32)33)20-24(21)12-11-23-9-7-19-31(5)26(14-15-27(23)31)22(2)8-6-18-30(3,4)35/h11-12,22,25-27,35H,1,6-10,13-20H2,2-5H3,(H,32,33)/b23-11+,24-12-/t22-,25+,26-,27+,31-/m1/s1
• InChIKey: XYAOPXNVLMIXNI-BPMXTZFCSA-N
• SMILES: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)OC(=O)CCC(=O)O)C

25-Hydroxyvitamin D3 3-Hemisuccinate is a derivative of 25-hydroxyvitamin D3, an active metabolite of vitamin D3 that plays a crucial role in calcium homeostasis and bone health. This compound is used in the study of vitamin D metabolism and its physiological effects. In pharmaceutical chemistry, it is employed in the development and evaluation of vitamin D analogues and supplements. The hemisuccinate moiety enhances its solubility and facilitates its conjugation to proteins for immunoassays, aiding in the precise measurement of vitamin D levels in biological samples. It is also used in research to investigate the mechanisms of vitamin D-mediated signaling pathways and their implications in various health conditions.