25,26-Dihydroxy Vitamin D3-d3

• CAT Number: R052219
• CAS Number: NA
• Molecular Formula: C₂₇H₄₁D₃O₃
• Molecular Weight: 419.65
• Purity: ≥95%
• Synonyms: (6R)-2-methyl-6-[(1R,3aS,4E,7aR)-octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-7a-methyl-1H-inden-1-yl]-1,2-Heptanediol-d3; (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25,26-triol-d3; 9,10-Secocholesta-5,7,10(19)-tri
• Storage: Room temperature
• IUPAC Name: (6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-(trideuteriomethyl)heptane-1,2-diol
• InChI: InChI=1S/C27H44O3/c1-19-9-12-23(29)17-22(19)11-10-21-8-6-16-27(4)24(13-14-25(21)27)20(2)7-5-15-26(3,30)18-28/h10-11,20,23-25,28-30H,1,5-9,12-18H2,2-4H3/b21-10+,22-11-/t20-,23+,24-,25+,26?,27-/m1/s1/i3D3
• InChIKey: QOWCBCXATJITSI-VROSBJPWSA-N
• SMILES: [2H]C([2H])([2H])C(CCC[C@@H](C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C)(CO)O

25,26-Dihydroxy Vitamin D3-d3 is a deuterium-labeled form of 25,26-dihydroxyvitamin D3, a metabolite of vitamin D3. The deuterium labeling aids in detailed studies of its metabolic pathways, distribution, and pharmacokinetics using techniques like mass spectrometry and NMR spectroscopy. This compound is critical in pharmaceutical and biomedical research, particularly in understanding vitamin D metabolism and its role in calcium homeostasis and bone health. It helps in investigating the effects of vitamin D derivatives on various biological processes, aiding in the development of treatments for conditions like osteoporosis and other metabolic bone diseases.