25,26-Dihydroxyvitamin D3

• CAT Number: I003018
• CAS Number: 29261-12-9
• Molecular Formula: C27H44O3
• Molecular Weight: 416.64
• Purity: ≥95%
• Synonyms: (6R)-6-[(1R,3aS,4E)-4-[(2E)-2-(5-hydroxy-2-methylidenecyclohexylidene)ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-1,2-diol
• Target: VD/VDR; Endogenous Metabolite
• Solubility: 10 mM in DMSO
• Storage: −20°C
• IUPAC Name: (6R)-6-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methylheptane-1,2-diol
• InChI: InChI=1S/C27H44O3/c1-19-9-12-23(29)17-22(19)11-10-21-8-6-16-27(4)24(13-14-25(21)27)20(2)7-5-15-26(3,30)18-28/h10-11,20,23-25,28-30H,1,5-9,12-18H2,2-4H3/b21-10+,22-11-/t20-,23+,24-,25+,26?,27-/m1/s1
• InChIKey: QOWCBCXATJITSI-ZLNGONTQSA-N
• SMILES: CC(CCCC(C)(CO)O)C1CCC2C1(CCCC2=CC=C3CC(CCC3=C)O)C

25,26-Dihydroxyvitamin D3 is a metabolite derived from vitamin D3. It exhibits activity in promoting intestinal calcium transport. This metabolite plays a role in regulating calcium homeostasis and bone metabolism. Enhancing the absorption of calcium from the intestines, it contributes to the maintenance of proper calcium levels in the body. This compound has been studied for its potential therapeutic applications in conditions associated with calcium deficiency or impaired calcium absorption, such as osteoporosis and hypocalcemia.