(25R)-Spirost-4-ene-3,12-dione

• CAT Number: I043276
• CAS Number: 6875-60-1
• Molecular Formula: C27H38O4
• Molecular Weight: 426.59
• Purity: ≥95%
• Synonyms: (1R,2S,4S,5’R,6R,7S,8R,9S,12S,13R)-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-ene-6,2′-oxane]-10,16-dione
• InChI: InChI=1S/C27H38O4/c1-15-7-10-27(30-14-15)16(2)24-22(31-27)12-21-19-6-5-17-11-18(28)8-9-25(17,3)20(19)13-23(29)26(21,24)4/h11,15-16,19-22,24H,5-10,12-14H2,1-4H3/t15-,16+,19-,20+,21+,22+,24+,25+,26-,27-/m1/s1
• InChIKey: ZVWYBBDTSJOAHD-HGMFYQPQSA-N
• SMILES: CC1CCC2(C(C3C(O2)CC4C3(C(=O)CC5C4CCC6=CC(=O)CCC56C)C)C)OC1

(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells[1].

Reference

[1]. P L Tsai, et al. Constituents and bioactive principles of Polygonum chinensis. Phytochemistry. 1998 Nov;49(6):1663-6.
 [Content Brief]