For research use only. Not for therapeutic Use.
2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent probe. 2,7-Dichlorodihydrofluorescein yields the highly fluorescent 2′,7′-dichlorofluorescein (DCF) that can be used for reactive oxygen species measurement[1][2].
| Catalog Number | M011679 |
| CAS Number | 106070-31-9 |
| Synonyms | 2-(2,7-dichloro-3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid |
| Molecular Formula | C20H12Cl2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C20H12Cl2O5/c21-13-5-11-17(7-15(13)23)27-18-8-16(24)14(22)6-12(18)19(11)9-3-1-2-4-10(9)20(25)26/h1-8,19,23-24H,(H,25,26) |
| InChIKey | XDFNWJDGWJVGGN-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)C2C3=CC(=C(C=C3OC4=CC(=C(C=C24)Cl)O)O)Cl)C(=O)O |
| Reference | [1]. Reiniers MJ, et al. Preparation and Practical Applications of 2′,7′-Dichlorodihydrofluorescein in Redox Assays. Anal Chem. 2017 Apr 4;89(7):3853-3857. [2]. Chen X, et al. 2′,7′-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res. 2010 Jun;44(6):587-604. |
