2,8-Dihydroxyadenine

• CAT Number: R044056
• CAS Number: 30377-37-8
• Molecular Formula: C5H5N5O2
• Molecular Weight: 167.128
• Purity: ≥95%
• Synonyms: 6-Amino-7,9-dihydro-2H-purine-2,8(3H)-dione; 6-amino-1H-Purine-2,8(3H,7H)-dione; 6-Amino-purine-2,8-diol; 2,8-Dihydroxyadenine; 2,8-Dioxyadenine; 6-Amino-1H-purine-2,8(3H,7H)-dione; 6-Amino-2,8-dihydroxypurine
• Target: Endogenous Metabolite
• Storage: -20°C
• IUPAC Name: 6-amino-7,9-dihydro-1H-purine-2,8-dione
• InChI: InChI=1S/C5H5N5O2/c6-2-1-3(9-4(11)7-1)10-5(12)8-2/h(H5,6,7,8,9,10,11,12)
• InChIKey: XFBOJHLYDJZYSP-UHFFFAOYSA-N
• SMILES: C12=C(NC(=O)N=C1NC(=O)N2)N

2,8-Dihydroxyadenine is a derivative of adenine, a fundamental component of DNA and RNA. This compound is notable in medical research for its role in adenine phosphoribosyltransferase deficiency, a rare genetic disorder leading to kidney stones and renal failure. Studying 2,8-dihydroxyadenine helps understand and develop treatments for related metabolic diseases, highlighting its significance in biochemical and clinical research.