(2S)-2-[[4-[(2-fluorophenyl)methoxy]phenyl]methylamino]propanamide

• CAT Number: M117811
• CAS Number: 133865-88-0
• Molecular Formula: C17H19FN2O2
• Molecular Weight: 302.349
• Purity: ≥95%
• Target: Sodium Channel
• Storage: -20°C
• IUPAC Name: (2S)-2-[[4-[(2-fluorophenyl)methoxy]phenyl]methylamino]propanamide
• InChI: InChI=1S/C17H19FN2O2/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18/h2-9,12,20H,10-11H2,1H3,(H2,19,21)/t12-/m0/s1
• InChIKey: BHJIBOFHEFDSAU-LBPRGKRZSA-N
• SMILES: CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC=CC=C2F

Priralfinamide, also known as Ralfinamide, FCE-26742A; NW-1029; PNU-0154339E, is a Na-channel blocker for the treatment of neuropathic pain and other pain conditions such as post-operative dental pain. It has a relatively complex pharmacology, acting as a mixed voltage-gated sodium channel blocker (including Nav1.7), N-type calcium channel blocker, noncompetitive NMDA receptor antagonist, and monoamine oxidase B inhibitor.

Reference

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