(2’S, 3’R)-Cabazitaxel

• CAT Number: R023198
• CAS Number: 1714967-27-7
• Molecular Formula: C45H57NO14
• Molecular Weight: 835.944
• Purity: ≥95%
• Storage: -20°C
• InChI: InChI=1S/C45H57NO14/c1-24-28(57-39(51)33(48)32(26-17-13-11-14-18-26)46-40(52)60-41(3,4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8,36(49)34(55-10)31(24)42(45,6)7)29(54-9)21-30-44(35,23-56-30)59-25(2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3,(H,46,52)/t28-,29-,30+,32+,33-,34+,35-,37-,43+,44-,45+/m0/s1
• InChIKey: BMQGVNUXMIRLCK-DVBUQMQDSA-N
• SMILES: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC

(2’S, 3’R)-Cabazitaxel is a semi-synthetic taxane derivative used in cancer therapy, particularly for metastatic hormone-refractory prostate cancer. This compound works by stabilizing microtubules, thereby inhibiting cell division and promoting apoptosis in cancer cells. Its improved solubility and efficacy compared to other taxanes enhance its therapeutic potential. (2’S, 3’R)-Cabazitaxel is administered via intravenous infusion and is often used when other treatments have failed, demonstrating its critical role in advanced cancer treatment protocols.