(2S)-Narirutin

• CAT Number: R042058
• CAS Number: 14259-46-2
• Molecular Formula: C27H32O14
• Molecular Weight: 580.54
• Purity: ≥95%
• Synonyms: (2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Narirutin; Isonaringenin; Isonaringin; Naringenin 7-O-Rutinoside; Naringenin 7-Rutinoside; Naringenin 7β-Rutinoside
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one
• InChI: InChI=1S/C27H32O14/c1-10-20(31)22(33)24(35)26(38-10)37-9-18-21(32)23(34)25(36)27(41-18)39-13-6-14(29)19-15(30)8-16(40-17(19)7-13)11-2-4-12(28)5-3-11/h2-7,10,16,18,20-29,31-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1
• InChIKey: HXTFHSYLYXVTHC-AJHDJQPGSA-N
• SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)O)O)O)O)O)O)O)O

(2S)-Narirutin（Cat No.:R042058）is a flavonoid glycoside predominantly found in citrus fruits. This naturally occurring compound exhibits various bioactive properties, including antioxidant, anti-inflammatory, and anticancer effects. (2S)-Narirutin is known for its potential in modulating metabolic pathways, improving vascular health, and reducing oxidative stress, making it a subject of interest in pharmacological research. Due to its ability to influence key cellular mechanisms, (2S)-Narirutin is explored for its therapeutic potential in managing chronic diseases such as cardiovascular disorders and diabetes. It offers a promising avenue for the development of functional foods and nutraceuticals.

Reference

1.Mizelle, J. W., et al. "Isolation and identification of some flavanone rutinosides of the grapefruit." Analytical biochemistry 12.2 (1965): 316-324.
2.Funaguchi, Norihiko, et al. "Narirutin inhibits airway inflammation in an allergic mouse model." Clinical and experimental pharmacology & physiology 34.8 (2007): 766-770.
3.Li, Yan, et al. "Narirutin produces antidepressant-like effects in a chronic unpredictable mild stress mouse model." Neuroreport 29.15 (2018): 1264-1268.