3β-Amino-3-deoxydigitoxigenin Hemisuccinate N-Succinimidyl Ester

• CAT Number: R046388
• CAS Number: 216299-46-6
• Molecular Formula: C31H42N2O9
• Molecular Weight: 586.68
• Purity: ≥95%
• Synonyms: (3β,5β,12β)-3-[[4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-1,4-dioxobutyl]amino]-12,14-dihydroxycard-20(22)-enolide
• Storage: -20°C
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 4-[[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]amino]-4-oxobutanoate
• InChI: InChI=1S/C31H42N2O9/c1-29-11-9-19(32-24(35)5-8-27(38)42-33-25(36)6-7-26(33)37)14-18(29)3-4-21-22(29)15-23(34)30(2)20(10-12-31(21,30)40)17-13-28(39)41-16-17/h13,18-23,34,40H,3-12,14-16H2,1-2H3,(H,32,35)/t18-,19+,20-,21-,22+,23-,29+,30+,31+/m1/s1
• InChIKey: AVQGRLJRQILBRQ-ZCIIQETRSA-N
• SMILES: CC12CCC(CC1CCC3C2CC(C4(C3(CCC4C5=CC(=O)OC5)O)C)O)NC(=O)CCC(=O)ON6C(=O)CCC6=O

3β-Amino-3-deoxydigitoxigenin Hemisuccinate N-Succinimidyl Ester(CAT: R046388) is a synthetic derivative of digitoxigenin, a cardiac glycoside that exhibits potent activity on the heart by inhibiting Na+/K+-ATPase. This specific compound is chemically modified to include an amino group and a hemisuccinate ester, which can be used for conjugation to proteins or other molecules through the succinimidyl ester group. It is commonly utilized in biochemical research, particularly for creating digitoxigenin-based probes or for studying the mechanisms of cardiac glycosides in cellular models. The succinimidyl ester moiety enables efficient attachment to amine groups in proteins, making it valuable for labeling or drug design purposes.