For research use only. Not for therapeutic Use.
3′-O-Methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
| Catalog Number | I041245 |
| CAS Number | 20594-00-7 |
| Synonyms | 4-amino-1-[(2R,3S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidin-2-one |
| Molecular Formula | C10H15N3O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C10H15N3O5/c1-17-8-5(4-14)18-9(7(8)15)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7+,8?,9-/m1/s1 |
| InChIKey | RZJCFLSPBDUNDH-DYZKPSFTSA-N |
| SMILES | COC1C(OC(C1O)N2C=CC(=NC2=O)N)CO |
| Reference | [1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. |
