3-(2,3-Dichlorobenzamido) Lamotrigine

• CAT Number: C000151
• CAS Number: 252186-79-1
• Molecular Formula: C₁₆H₉Cl₄N₅O
• Molecular Weight: 429.08
• Purity: ≥95%
• Synonyms: N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide; Lamotrigine EP Impurity F
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• Appearance: White to Off-White Solid
• Storage: -20°C, Inert atmosphere, Light sensitive

3-(2,3-Dichlorobenzamido) Lamotrigine (CAT: C000151), also known as Lamotrigine EP Impurity F, is an impurity associated with the anticonvulsant medication Lamotrigine. This compound is formed as a byproduct during the synthesis of Lamotrigine. Monitoring and controlling the levels of such impurities are critical in the pharmaceutical industry to ensure the purity and safety of the final drug product.

Reference

Emami, J. et al.: J. Pharmac. Biomed. Anal., 40, 999 (2006); Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);