3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole

• CAT Number: R067349
• CAS Number: 340267-36-9
• Molecular Formula: C17H12F3NO3S
• Molecular Weight: 367.34
• Purity: ≥95%
• Synonyms: 3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole
• Target: PI3K/Akt/mTOR
• Storage: -20°C
• IUPAC Name: 3-(4-methylsulfonylphenyl)-4-phenyl-5-(trifluoromethyl)-1,2-oxazole
• InChI: InChI=1S/C17H12F3NO3S/c1-25(22,23)13-9-7-12(8-10-13)15-14(11-5-3-2-4-6-11)16(24-21-15)17(18,19)20/h2-10H,1H3
• InChIKey: KKBWWVXRKULXHF-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)C1=CC=C(C=C1)C2=NOC(=C2C3=CC=CC=C3)C(F)(F)F

3-[4-(Methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole (Cat No.: R067349) is an organic compound with a distinct isoxazole ring structure, substituted with a methylsulfonyl group, phenyl groups, and a trifluoromethyl group. This compound has potential biological activity, particularly in the areas of anti-inflammatory, antimicrobial, and anticancer research. The trifluoromethyl group enhances its stability and lipophilicity, making it a promising lead for drug development. Its structure suggests it may interact with specific enzymes or receptors, though more studies are needed to fully explore its therapeutic applications.

Reference

1.Barnett, J.,Chow, J.,Ives, D., et al. Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system. Biochim Biophys. Acta. 1209(1), 130-139 (1994).