3-Aminorifamycin S (Technical Grade)

• CAT Number: C000388
• CAS Number: 51756-80-0
• Molecular Formula: C₃₇H₄₆N₂O₁₂
• Molecular Weight: 710.77
• Purity: ≥95%
• Synonyms: 3-Amino-1,4-dideoxy-1,4-dihydro-1,4-dioxorifamycin
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Appearance: Dark Brown to Black Solid
• Storage: -20°C, Hygroscopic, Light sensitive
• IUPAC Name: [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-amino-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27,29-tetraoxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25-heptaen-13-yl] acetate
• InChI: InChI=1S/C37H46N2O12/c1-15-11-10-12-16(2)36(47)39-27-26(38)31(44)23-24(32(27)45)30(43)20(6)34-25(23)35(46)37(8,51-34)49-14-13-22(48-9)17(3)33(50-21(7)40)19(5)29(42)18(4)28(15)41/h10-15,17-19,22,28-29,33,41-43H,38H2,1-9H3,(H,39,47)/b11-10+,14-13+,16-12-/t15-,17+,18+,19+,22-,28-,29+,33+,37-/m0/s1
• InChIKey: SMPJCQGFZSDIHE-GVDHMVJUSA-N
• SMILES: C[C@H]1/C=C/C=C(\C(=O)NC2=C(C(=O)C3=C(C2=O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)N)/C

3-Aminorifamycin S(CAT: C000388) is a derivative of the rifamycin antibiotic family, recognized for its potent antimicrobial activity. By targeting bacterial RNA polymerase, it inhibits transcription, effectively suppressing the growth of various bacterial pathogens, including resistant strains. 3-Aminorifamycin S is particularly significant in infectious disease research, where it is used to study the mechanisms of antibiotic action and resistance, as well as to explore its potential as a lead compound for developing new antibiotics. Its unique structure and activity make it a valuable tool for advancing antimicrobial strategies in the fight against bacterial infections.