For research use only. Not for therapeutic Use.
Useful building block for the synthesis of FP-TZTP
KEYWORDS: 3-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole | supplier | Building block | CAS [131986-28-2] | FP-TZTP | [18F]-FP-TZTP | muscarinic | M2 | PET | precursor | positron emission tomography
| Catalog Number | M113461 |
| CAS Number | 131986-28-2 |
| Molecular Formula | C7H4ClN3S |
| Purity | ≥95% |
| IUPAC Name | 3-chloro-4-pyridin-3-yl-1,2,5-thiadiazole |
| InChI | InChI=1S/C7H4ClN3S/c8-7-6(10-12-11-7)5-2-1-3-9-4-5/h1-4H |
| SMILES | C1=CC(=CN=C1)C2=NSN=C2Cl |
| Reference | P Sauerberg et al. Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines. J Med Chem. 1992 Jun 12;35(12):2274-83.
DO Kiesewetter et al. The automated radiosynthesis of [18F]FP-TZTP. Nucl Med Biol. 2003 Jan;30(1):73-7. |
