3-Cyano-7-ethoxycoumarin

• CAT Number: I000627
• CAS Number: 117620-77-6
• Molecular Formula: C12H9NO3
• Molecular Weight: 215.20
• Purity: ≥95%
• Synonyms: 7-ethoxy-2-oxo-2H-chromene-3-carbonitrile
• Target: Cytochrome P450
• Solubility: DMSO:15mg/mL
• Storage: 2-8°C
• IUPAC Name: 7-ethoxy-2-oxochromene-3-carbonitrile
• InChI: InChI=1S/C12H9NO3/c1-2-15-10-4-3-8-5-9(7-13)12(14)16-11(8)6-10/h3-6H,2H2,1H3
• InChIKey: YAFGHMIAFYQSCF-UHFFFAOYSA-N
• SMILES: CCOC1=CC2=C(C=C1)C=C(C(=O)O2)C#N

3-Cyano-7-ethoxycoumarin（Cat No.:I000627）is a synthetic coumarin derivative widely utilized in biochemical assays, particularly as a fluorogenic substrate for cytochrome P450 enzymes. Upon enzymatic cleavage, it releases a fluorescent signal, making it valuable for studying enzyme activity, drug metabolism, and inhibitor screening in drug discovery. Its high sensitivity and compatibility with fluorescence-based detection methods make it ideal for assessing the activity of specific P450 isoforms in vitro. Due to its robust and consistent fluorescence response, 3-Cyano-7-ethoxycoumarin supports research in pharmacokinetics and toxicology.