3-Deschloro-3,4-difluoro Gefitinib

• CAT Number: C000773
• CAS Number: 184475-50-1
• Molecular Formula: C₂₂H₂₄F₂N₄O₃
• Molecular Weight: 430.45
• Purity: ≥95%
• Synonyms: N-(3,4-Difluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• Appearance: Off-White to Pale Yellow Solid
• Storage: -20°C, Inert atmosphere
• IUPAC Name: N-(3,4-difluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
• InChI: InChI=1S/C22H24F2N4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-17(23)18(24)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
• InChIKey: JACDFLVHUYYSBS-UHFFFAOYSA-N
• SMILES: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)F)OCCCN4CCOCC4

3-Deschloro-3,4-difluoro gefitinib (Cat No.:C000773 ) is a derivative of gefitinib, a tyrosine kinase inhibitor used in cancer therapy. This compound likely holds significance in medicinal chemistry and drug development. Its modified structure suggests potential alterations in pharmacological properties. Researchers may investigate its effects on receptor tyrosine kinases, particularly the epidermal growth factor receptor (EGFR), and its potential therapeutic applications.

Reference

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