3-Desmethyl Gatifloxacin-d8

• CAT Number: R056475
• CAS Number: 1794941-53-9
• Molecular Formula: C18H20FN3O4
• Molecular Weight: 369.422
• Purity: ≥95%
• Synonyms: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid; AM 1147-d8; PD 135042-d8
• Storage: Store at -20°C
• IUPAC Name: 1-cyclopropyl-6-fluoro-8-methoxy-7-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• InChI: InChI=1S/C18H20FN3O4/c1-26-17-14-11(8-13(19)15(17)21-6-4-20-5-7-21)16(23)12(18(24)25)9-22(14)10-2-3-10/h8-10,20H,2-7H2,1H3,(H,24,25)/i4D2,5D2,6D2,7D2
• InChIKey: XJCSNIFKGXSDGN-DUSUNJSHSA-N
• SMILES: COC1=C2C(=CC(=C1N3CCNCC3)F)C(=O)C(=CN2C4CC4)C(=O)O

3-Desmethyl Gatifloxacin-d8 is a deuterated derivative of 3-desmethyl gatifloxacin, a metabolite of the fluoroquinolone antibiotic gatifloxacin. In this compound, eight hydrogen atoms are replaced with deuterium, making it especially useful in pharmacokinetic and metabolic studies. The deuterium labeling allows for precise detection and analysis in mass spectrometry and NMR spectroscopy, facilitating the study of drug metabolism, distribution, and excretion. Despite the isotopic modification, it retains the biological properties of the non-deuterated metabolite, making it valuable for detailed research in drug development and pharmacology.