For research use only. Not for therapeutic Use.
A very potent and selective ligand for the D<sub>2</sub> receptor (K<sub>i</sub> = 0.023 nM). Compared with spiperone, displays a 2.5-fold greater affinity at D<sub>2</sub> and a 12-fold lower affinity at 5-HT<sub>2</sub> receptors.
| Catalog Number | I010280 |
| CAS Number | 1135278-61-3 |
| Synonyms | 8-[4-(4-Fluorophenyl)-4-oxobutyl]-(3-fluorobenzyl-1-phenyl)-1,3,8-triazaspiro[4,5]decan-4-one maleate |
| Molecular Formula | C34H35F2N3O6 |
| Purity | ≥95% |
| Target | Dopamine Receptor |
| Solubility | Soluble in DMSO |
| Storage | Store at RT |
| IUPAC Name | (Z)-but-2-enedioic acid;3-[(3-fluorophenyl)methyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| InChI | InChI=1S/C30H31F2N3O2.C4H4O4/c31-25-13-11-24(12-14-25)28(36)10-5-17-33-18-15-30(16-19-33)29(37)34(21-23-6-4-7-26(32)20-23)22-35(30)27-8-2-1-3-9-27;5-3(6)1-2-4(7)8/h1-4,6-9,11-14,20H,5,10,15-19,21-22H2;1-2H,(H,5,6)(H,7,8)/b;2-1- |
| InChIKey | JURUFADWVGXLOY-BTJKTKAUSA-N |
| SMILES | C1CN(CCC12C(=O)N(CN2C3=CC=CC=C3)CC4=CC(=CC=C4)F)CCCC(=O)C5=CC=C(C=C5)F.C(=CC(=O)O)C(=O)O |
