For research use only. Not for therapeutic Use.
3-Fucosyllactose (3-Fucosyl-D-lactose) is one of the major fucosylated oligosaccharides found in human breast milk. 3-Fucosyllactose shows prebiotic, immunomodulator, neonatal brain development, and antimicrobial function[1].
3-Fucosyllactose (3-Fucosyl-D-lactose) (10 mg/mL) can inhibit the adhesion of enteric and respiratory pathogens to the human epithelial cell lines Caco-2 and A549[2].
| Catalog Number | R068569 |
| CAS Number | 41312-47-4 |
| Synonyms | (2R,3R,4R,5R)-2,5,6-trihydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhexanal |
| Molecular Formula | C18H32O15 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H32O15/c1-5-9(24)11(26)13(28)17(30-5)32-15(6(22)2-19)16(7(23)3-20)33-18-14(29)12(27)10(25)8(4-21)31-18/h2,5-18,20-29H,3-4H2,1H3/t5-,6-,7+,8+,9+,10-,11+,12-,13-,14+,15+,16+,17-,18-/m0/s1 |
| InChIKey | OVYANALZSAYBOJ-XOGIJULASA-N |
| SMILES | CC1C(C(C(C(O1)OC(C(C=O)O)C(C(CO)O)OC2C(C(C(C(O2)CO)O)O)O)O)O)O |
| Reference | [1]. Choi YH, et al. Biosynthesis of the human milk oligosaccharide 3-fucosyllactose in metabolically engineered Escherichia coli via the salvage pathway through increasing GTP synthesis and β-galactosidase modification. Biotechnol Bioeng. 2019 Dec;116(12):3324-3332. [2]. Weichert S, et al. Bioengineered 2′-fucosyllactose and 3-fucosyllactose inhibit the adhesion of Pseudomonas aeruginosa and enteric pathogens to human intestinal and respiratory cell lines. Nutr Res. 2013 Oct;33(10):831-8. |
