3-Hydroxy agomelatine-d3

• CAT Number: S000476
• CAS Number: 1079774-23-4
• Molecular Formula: C15H14D3NO3
• Molecular Weight: 262.32
• Purity: ≥95%
• IUPAC Name: N-[2-[3-hydroxy-7-(trideuteriomethoxy)naphthalen-1-yl]ethyl]acetamide
• InChI: InChI=1S/C15H17NO3/c1-10(17)16-6-5-12-8-13(18)7-11-3-4-14(19-2)9-15(11)12/h3-4,7-9,18H,5-6H2,1-2H3,(H,16,17)/i2D3
• InChIKey: VUBBOOVHTBZRTJ-BMSJAHLVSA-N
• SMILES: CC(=O)NCCC1=C2C=C(C=CC2=CC(=C1)O)OC

3-Hydroxy agomelatine-d3（Cat No.:S000476） is a deuterated form of 3-Hydroxy agomelatine, where three hydrogen atoms are replaced with deuterium. This modification aims to study the compound’s metabolic stability and pharmacokinetics in greater detail. 3-Hydroxy agomelatine is a metabolite of agomelatine, a medication primarily used to treat major depressive disorder. Agomelatine functions as a melatonin receptor agonist and a 5-HT2C receptor antagonist, influencing circadian rhythms and mood regulation. The deuterated version, 3-Hydroxy agomelatine-d3, helps researchers understand how the body processes and breaks down the drug, providing insights into its efficacy and safety profile.