3-Hydroxy Detomidine Hydrochloride

• CAT Number: R051573
• CAS Number: 1794759-72-0
• Molecular Formula: C12H15ClN2O
• Molecular Weight: 238.715
• Purity: ≥95%
• Synonyms: 3-(1H-Imidazol-5-ylmethyl)-2-methylbenzenemethanol Hydrochloride; 3-(1H-Imidazol-4-ylmethyl)-2-methylbenzenemethanol Hydrochloride
• Storage: Desiccate at +4 ℃
• IUPAC Name: [3-(1H-imidazol-5-ylmethyl)-2-methylphenyl]methanol;hydrochloride
• InChI: InChI=1S/C12H14N2O.ClH/c1-9-10(3-2-4-11(9)7-15)5-12-6-13-8-14-12;/h2-4,6,8,15H,5,7H2,1H3,(H,13,14);1H
• InChIKey: JHQUAWVVRURKMP-UHFFFAOYSA-N
• SMILES: CC1=C(C=CC=C1CO)CC2=CN=CN2.Cl

3-Hydroxy detomidine hydrochloride is a metabolite of detomidine, a sedative and analgesic agent used in veterinary medicine. This compound is formed in the liver during detomidine metabolism. 3-Hydroxy detomidine exhibits similar pharmacological effects to detomidine but with reduced potency. Research on this metabolite focuses on its pharmacokinetics, pharmacodynamics, and contribution to the overall clinical profile of detomidine. Understanding its role aids in optimizing dosage regimens and improving safety in veterinary anesthesia and sedation protocols.