3-Hydroxypropionaldehyde

For research use only. Not for therapeutic Use.

  • CAT Number: M015349
  • CAS Number: 2134-29-4
  • Molecular Formula: C3H6O2
  • Molecular Weight: 74.08
  • Purity: ≥95%
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3-Hydroxypropionaldehyde(Cat No.:M015349), also known as reuterin, is a naturally occurring compound produced by certain Lactobacillus species during glycerol fermentation. Recognized for its broad-spectrum antimicrobial properties, it is effective against various bacteria, fungi, and viruses, making it valuable in food preservation and probiotics. 3-Hydroxypropionaldehyde acts by inhibiting microbial growth through interactions with cellular components, helping to extend the shelf life of food products. Its role in gut health is also under study, as it may support beneficial bacteria and inhibit pathogens, contributing to its potential in food safety and biotechnological applications.


Catalog Number M015349
CAS Number 2134-29-4
Synonyms

3-hydroxypropionaldehyde;3-Hydroxypropanal;BETA-HYDROXYPROPIONALDEHYDE;β-Hydroxypropanal;C00969;Propanal, 3-hydroxy-;5g – 10g – 25g;3-Oxo-1-propanol

Molecular Formula C3H6O2
Purity ≥95%
Target Bacterial
Storage -20°C
IUPAC Name 3-hydroxypropanal
InChI InChI=1S/C3H6O2/c4-2-1-3-5/h2,5H,1,3H2
InChIKey AKXKFZDCRYJKTF-UHFFFAOYSA-N
SMILES C(CO)C=O
Reference

1: Zaushitsyna O, Dishisha T, Hatti-Kaul R, Mattiasson B. Crosslinked,
cryostructured Lactobacillus reuteri monoliths for production of
3-hydroxypropionaldehyde, 3-hydroxypropionic acid and 1,3-propanediol from
glycerol. J Biotechnol. 2017 Jan 10;241:22-32. doi:
10.1016/j.jbiotec.2016.11.005. Epub 2016 Nov 6. PubMed PMID: 27829124.
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2: Maervoet VE, De Maeseneire SL, Avci FG, Beauprez J, Soetaert WK, De Mey M.
High yield 1,3-propanediol production by rational engineering of the
3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii. Microb Cell Fact.
2016 Jan 28;15:23. doi: 10.1186/s12934-016-0421-y. PubMed PMID: 26822953; PubMed
Central PMCID: PMC4731958.
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3: Sabet-Azad R, Sardari RR, Linares-Pastén JA, Hatti-Kaul R. Production of
3-hydroxypropionic acid from 3-hydroxypropionaldehyde by recombinant Escherichia
coli co-expressing Lactobacillus reuteri propanediol utilization enzymes.
Bioresour Technol. 2015 Mar;180:214-21. doi: 10.1016/j.biortech.2014.12.109. Epub
2015 Jan 7. PubMed PMID: 25614245.
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4: Sardari RR, Dishisha T, Pyo SH, Hatti-Kaul R. Semicarbazide-functionalized
resin as a new scavenger for in situ recovery of 3-hydroxypropionaldehyde during
biotransformation of glycerol by Lactobacillus reuteri. J Biotechnol. 2014 Dec
20;192 Pt A:223-30. PubMed PMID: 25456063.
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5: Su M, Li Y, Ge X, Tian P. 3-Hydroxypropionaldehyde-specific aldehyde
dehydrogenase from Bacillus subtilis catalyzes 3-hydroxypropionic acid production
in Klebsiella pneumoniae. Biotechnol Lett. 2015 Mar;37(3):717-24. doi:
10.1007/s10529-014-1730-z. Epub 2014 Nov 20. PubMed PMID: 25409630.
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6: Dishisha T, Pereyra LP, Pyo SH, Britton RA, Hatti-Kaul R. Flux analysis of the
Lactobacillus reuteri propanediol-utilization pathway for production of
3-hydroxypropionaldehyde, 3-hydroxypropionic acid and 1,3-propanediol from
glycerol. Microb Cell Fact. 2014 May 27;13:76. doi: 10.1186/1475-2859-13-76.
PubMed PMID: 24886501; PubMed Central PMCID: PMC4045878.
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7: Tajima T, Fuki K, Kataoka N, Kudou D, Nakashimada Y, Kato J. Construction of a
simple biocatalyst using psychrophilic bacterial cells and its application for
efficient 3-hydroxypropionaldehyde production from glycerol. AMB Express. 2013
Dec 5;3(1):69. doi: 10.1186/2191-0855-3-69. PubMed PMID: 24314120; PubMed Central
PMCID: PMC4029479.

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