For research use only. Not for therapeutic Use.
3′-Methoxypuerarin (3′-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity.
3′-Methoxypuerarin increases the number of surviving neurons in the hippocampal CA1 region and markedly reduces the number of apoptotic pyramidal neurons after ischemia/reperfusion injury. 3′-Methoxypuerarin can protect hippocampal neurons against I/R injury by inhibiting apoptosis[1].
| Catalog Number | M016418 |
| CAS Number | 117047-07-1 |
| Synonyms | 7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one |
| Molecular Formula | C22H22O10 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H22O10/c1-30-14-6-9(2-4-12(14)24)11-8-31-21-10(17(11)26)3-5-13(25)16(21)22-20(29)19(28)18(27)15(7-23)32-22/h2-6,8,15,18-20,22-25,27-29H,7H2,1H3/t15-,18-,19+,20-,22+/m1/s1 |
| InChIKey | HQQUZVFMUSCUJS-PGPONNFDSA-N |
| SMILES | COC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(C(O4)CO)O)O)O)O)O |
| Reference | [1]. Liu Y, et al. Protection by 3′-methoxypuerarin of rat hippocampal neurons against ischemia/reperfusion injury. Chin J Physiol. 2010 Apr 30;53(2):136-40. |
