3-N-Maleimidobenzoic Acid N-Succinimidyl Ester

• CAT Number: R000798
• CAS Number: 58626-38-3
• Molecular Formula: C15H10N2O6
• Molecular Weight: 314.253
• Purity: ≥95%
• Synonyms: 3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)benzoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; m-Maleimidobenzoyl-N-hydroxysuccinimide; NSC 294786; MBS
• Storage: -20°C
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)benzoate
• InChI: InChI=1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2
• InChIKey: LLXVXPPXELIDGQ-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)C2=CC(=CC=C2)N3C(=O)C=CC3=O

3-N-Maleimidobenzoic acid N-succinimidyl ester (Cat No.:R000798) is a chemical compound. It features a maleimide group attached to a benzoic acid core and a succinimidyl ester group that enhances its reactivity. This compound is crucial in bioconjugation and chemical research as a crosslinking agent for labeling proteins and other biomolecules. The maleimide moiety reacts selectively with thiols in biomolecules, enabling site-specific modification. The succinimidyl ester enhances the compound’s ability to form stable amide bonds with primary amines. 3-N-Maleimidobenzoic acid N-succinimidyl ester supports advancements in biochemistry, enabling the creation of labeled biomolecules for various analytical and biotechnological applications.