3-Nitrocoumarin

• CAT Number: I019233
• CAS Number: 28448-04-6
• Molecular Formula: C9H5NO4
• Molecular Weight: 191.14
• Purity: ≥95%
• Synonyms: 3-nitrochromen-2-one
• InChI: InChI=1S/C9H5NO4/c11-9-7(10(12)13)5-6-3-1-2-4-8(6)14-9/h1-5H
• InChIKey: YTCVPEZECJYZRK-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C=C(C(=O)O2)[N+](=O)[O-]

3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor[1].

Reference

[1]. Ward PD, et al. Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. J Biol Chem. 2002 Sep 20;277(38):35760-5.
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