For research use only. Not for therapeutic Use.
3-O-Methyl-N-acetyl-D-glucosamine is a potent inhibitor of N-acetylglucosamine kinase. 3-O-Methyl-N-acetyl-D-glucosamine potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine[1].
| Catalog Number | R000644 |
| CAS Number | 94825-74-8 |
| Synonyms | N-[(2R,3R,4R,5R)-4,5,6-trihydroxy-3-methoxy-1-oxohexan-2-yl]acetamide |
| Molecular Formula | C9H17NO6 |
| Purity | ≥95% |
| InChI | InChI=1S/C9H17NO6/c1-5(13)10-6(3-11)9(16-2)8(15)7(14)4-12/h3,6-9,12,14-15H,4H2,1-2H3,(H,10,13)/t6-,7+,8+,9+/m0/s1 |
| InChIKey | MFMCOGWYKDICDI-JQCXWYLXSA-N |
| SMILES | CC(=O)NC(C=O)C(C(C(CO)O)O)OC |
| Reference | [1]. Miwa I, et al. Utility of 3-O-methyl-N-acetyl-D-glucosamine, an N-acetylglucosamine kinase inhibitor, for accurate assay of glucokinase in pancreatic islets and liver. Enzyme Protein. 1994;48(3):135-142. |
