3'-O-(t-butyldimethylsilyl)thymidine

• CAT Number: L022145
• CAS Number: 40733-27-5
• Molecular Formula: C16H28N2O5Si
• Molecular Weight: 356.49
• Purity: ≥95%
• IUPAC Name: 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• InChI: InChI=1S/C16H28N2O5Si/c1-10-8-18(15(21)17-14(10)20)13-7-11(12(9-19)22-13)23-24(5,6)16(2,3)4/h8,11-13,19H,7,9H2,1-6H3,(H,17,20,21)/t11-,12+,13+/m0/s1
• InChIKey: QAPSNMNOIOSXSQ-YNEHKIRRSA-N

3′-O-(t-butyldimethylsilyl)thymidine (Cat.No:L022145) is a modified nucleoside used in nucleic acid synthesis. Its thymidine base is protected by a t-butyldimethylsilyl group at the 3′ position. This silylation protects the nucleoside during chemical reactions and can be subsequently removed, allowing controlled modification of nucleic acids for research or therapeutic purposes.