3-Oxo Atorvastatin

• CAT Number: I017319
• CAS Number: 887196-30-7
• Molecular Formula: C₃₃H₃₃FN₂O₅
• Molecular Weight: 556.62
• Purity: ≥95%
• Target: Drug Metabolite
• IUPAC Name: (5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-5-hydroxy-3-oxoheptanoic acid
• InChI: InChI=1S/C33H33FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26,37H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-/m1/s1
• InChIKey: JVFCMPKBFPIOON-AREMUKBSSA-N
• SMILES: CC(C)C1=C(C(=C(N1CC[C@H](CC(=O)CC(=O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4

3-Oxo Atorvastatin (Cat.No: I017319) is an impurity of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.

Reference

[1]. Ramesha, B., et al. DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING GRADIENT RP-UHPLC METHOD FOR THE DETERMINATION OF IMPURITIES IN ATORVASTATIN DRUG SUBSTANCE. Journal of Liquid Chromatography & Related Technologies.2013; 37(3), 275–297.