3-(Trifluoromethyl)-5-fluorophenylboronic acid pinacol ester

• CAT Number: L010208
• CAS Number: 627525-87-5
• Molecular Formula: C13H15BF4O2
• Molecular Weight: 290.06
• Purity: ≥95%
• IUPAC Name: 2-[3-fluoro-5-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• InChI: InChI=1S/C13H15BF4O2/c1-11(2)12(3,4)20-14(19-11)9-5-8(13(16,17)18)6-10(15)7-9/h5-7H,1-4H3
• InChIKey: BCRDVCMEIWHGRS-UHFFFAOYSA-N
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC(=C2)F)C(F)(F)F

3-(Trifluoromethyl)-5-fluorophenylboronic acid pinacol ester is a boronic ester featuring a trifluoromethyl group and a fluorophenyl moiety, linked through a pinacol ester structure. This compound is significant in organic synthesis, particularly in cross-coupling reactions, such as Suzuki-Miyaura coupling, to form complex organic molecules. The trifluoromethyl and fluorine substituents enhance its reactivity and influence its electronic properties. Its unique structure makes it valuable for developing pharmaceuticals and agrochemicals, with potential applications in medicinal chemistry and materials science.