3,3’-Diiodo-L-thyronine

• CAT Number: R000847
• CAS Number: 4604-41-5
• Molecular Formula: C15H13I2NO4
• Molecular Weight: 525.081
• Purity: ≥95%
• Synonyms: 3,3’-T2; O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine; 3-[4-(4-Hydroxy-3-iodophenoxy)-3-iodophenyl]-L-alanine
• Target: Immunology/Inflammation
• Storage: -20°C
• IUPAC Name: (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
• InChI: InChI=1S/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)/t12-/m0/s1
• InChIKey: CPCJBZABTUOGNM-LBPRGKRZSA-N
• SMILES: C1=CC(=C(C=C1CC(C(=O)O)N)I)OC2=CC(=C(C=C2)O)I

3,3/’-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.