3,3’-Dithio(succinimidyl propionate)

• CAT Number: R051067
• CAS Number: 57757-57-0
• Molecular Formula: C14H16N2O8S2
• Molecular Weight: 404.408
• Purity: ≥95%
• Synonyms: 1,1’-[Dithiobis[(1-oxo-3,1-propanediyl)oxy]]bis-2,5-pyrrolidinedione, Bis[2-[(succinimidyloxy)carbonyl]ethyl] disulfide; DTSP; Lomant’s Reagent; NSC 328386
• Target: ADC Linker
• Storage: Store at -20°C
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-[[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropyl]disulfanyl]propanoate
• InChI: InChI=1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
• InChIKey: FXYPGCIGRDZWNR-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCSSCCC(=O)ON2C(=O)CCC2=O

3,3′-Dithio(succinimidyl propionate) (Cat.No:R051067) is a crosslinking reagent commonly used in bioconjugation and protein chemistry. It contains two reactive maleimide groups that can form stable thioether bonds with cysteine residues on proteins. This compound is valuable in the development of protein-protein interactions, antibody labeling, and immunoassays.