3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate

• CAT Number: R056340
• CAS Number: 31135-55-4
• Molecular Formula: C15H12I3NO7S
• Molecular Weight: 731.034
• Purity: ≥95%
• Synonyms: Triiodothyronine Sulfate; 3,5-Diiodo-O-[3-iodo-4-(sulfooxy)phenyl]-L-tyrosine; 3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-L-alanine Hydrogen Sulfate; Triiodothyronine Hydrogen Sulfate; Liothyronine Sulfate; T3 Sulfate
• Target: Drug Metabolite
• Storage: -20°C
• IUPAC Name: (2S)-2-amino-3-[3,5-diiodo-4-(3-iodo-4-sulfooxyphenoxy)phenyl]propanoic acid
• InChI: InChI=1S/C15H12I3NO7S/c16-9-6-8(1-2-13(9)26-27(22,23)24)25-14-10(17)3-7(4-11(14)18)5-12(19)15(20)21/h1-4,6,12H,5,19H2,(H,20,21)(H,22,23,24)/t12-/m0/s1
• InChIKey: XBQYQXVJBNDCGY-LBPRGKRZSA-N
• SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)OS(=O)(=O)O

3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate is a sulfated derivative of triiodothyronine (T3), an active thyroid hormone crucial for regulating metabolism, growth, and development. This metabolite is formed through the sulfation of T3, which may alter its activity and bioavailability. While T3 is well-known for its role in modulating metabolic processes, the sulfate conjugate is less active but still significant in thyroid hormone metabolism and deactivation pathways. Studying this compound helps in understanding the complex regulation of thyroid hormones and their implications in thyroid-related disorders.