3,4-Dihydro-3-oxo-2-pyrazinecarboxamide

• CAT Number: R018060
• CAS Number: 55321-99-8
• Molecular Formula: C5H5N3O2
• Molecular Weight: 139.11
• Purity: ≥95%
• Synonyms: 3-Hydroxypyrazinamide; 3,4-Dihydro-3-oxo-pyrazinecarboxamide; 3-Hydroxy-2-pyrazinecarboxamide; NSC 163503; T 1105
• Target: Flavivirus
• Storage: RT
• IUPAC Name: 2-oxo-1H-pyrazine-3-carboxamide
• InChI: InChI=1S/C5H5N3O2/c6-4(9)3-5(10)8-2-1-7-3/h1-2H,(H2,6,9)(H,8,10)
• InChIKey: SZPBAPFUXAADQV-UHFFFAOYSA-N
• SMILES: C1=CN=C(C(=O)N1)C(=O)N

3,4-Dihydro-3-oxo-2-pyrazinecarboxamide（Cat No.:R018060）, also known as pyrazinamide, is an essential anti-tuberculosis drug with unique activity against Mycobacterium tuberculosis, especially in latent infections. It functions by disrupting fatty acid synthesis within the bacteria, leading to cell death. Pyrazinamide is widely studied for its ability to shorten TB treatment duration and combat resistant strains. In research, it plays a key role in investigating tuberculosis resistance mechanisms and optimizing combination therapies. Its effectiveness in targeting dormant bacterial populations makes it invaluable in TB eradication efforts and drug development.