3,4-Dimethoxycinnamic Acid

• CAT Number: R026426
• CAS Number: 2316-26-9
• Molecular Formula: C11H12O4
• Molecular Weight: 208.213
• Purity: ≥95%
• Synonyms: 3,4-Di-O-methylcaffeic Acid; 3,4-Dimethoxycinnamic Acid; 3,4-Dimethoxyphenyl-2-propenoic Acid; 3-(3,4-Dimethoxyphenyl)-2-propenoic Acid;?3-(3,4-Dimethoxyphenyl)acrylic Acid; 3’,4’-Dimethoxycinnamic Acid; Caffeic Acid Dimethyl Ether; Methylferulic Aci
• Storage: -20°C
• IUPAC Name: (E)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid
• InChI: InChI=1S/C11H12O4/c1-14-9-5-3-8(4-6-11(12)13)7-10(9)15-2/h3-7H,1-2H3,(H,12,13)/b6-4+
• InChIKey: HJBWJAPEBGSQPR-GQCTYLIASA-N
• SMILES: COC1=C(C=C(C=C1)C=CC(=O)O)OC

3,4-Dimethoxycinnamic Acid (CAS 2316-26-9) s a Cinnamic Acid derivative,used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids.

Reference

1.Kunishima, Munetaka, et al. "4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride: an efficient condensing agent leading to the formation of amides and esters." Tetrahedron 55.46 (1999): 13159-13170.
2.Xia, Qinqin, et al. "Copper-catalyzed N-methylation of amides and O-methylation of carboxylic acids by using peroxides as the methylating reagents." Organic letters 15.13 (2013): 3326-3329.