3,4-Epoxy-moxidectin

• CAT Number: C000652
• CAS Number: 1402163-94-3
• Molecular Formula: C₃₇H₅₃NO₉
• Molecular Weight: 655.82
• Purity: ≥95%
• Synonyms: (3R,4S,6R,23E,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-3,4:6,28-diepoxy-3,4-dihydro-23-(methoxyimino)milbemycin B
• Solubility: Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
• Appearance: White to Off-White Solid
• Storage: -20°C
• IUPAC Name: (1R,4S,4'Z,5'S,6R,6'S,10E,13R,14E,16E,20R,21S,22S,24R,25S)-21,25-dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-[(E)-4-methylpent-2-en-2-yl]spiro[3,7,19,23-tetraoxapentacyclo[15.7.1.14,8.020,25.022,24]hexacosa-10,14,16-triene-6,2'-oxane]-2-one
• InChI: InChI=1S/C37H53NO9/c1-20(2)14-23(5)30-24(6)28(38-42-8)18-36(46-30)17-27-16-26(45-36)13-12-22(4)15-21(3)10-9-11-25-19-43-33-31(39)35(7)32(47-35)29(34(40)44-27)37(25,33)41/h9-12,14,20-21,24,26-27,29-33,39,41H,13,15-19H2,1-8H3/b10-9+,22-12+,23-14+,25-11+,38-28-/t21-,24-,26?,27-,29-,30+,31-,32+,33+,35-,36-,37+/m0/s1
• InChIKey: NRMIMVNNJHFYQY-ZGEKGCJISA-N
• SMILES: C[C@@H]\1C/C(=C/CC2C[C@@H](C[C@@]3(O2)C/C(=N/OC)/[C@@H]([C@H](O3)/C(=C/C(C)C)/C)C)OC(=O)[C@@H]4[C@@H]5[C@@](O5)([C@H]([C@@H]6[C@]4(/C(=C/C=C1)/CO6)O)O)C)/C

3,4-Epoxy-moxidectin (Cat No.:C000652) is a derivative of moxidectin, a veterinary anthelmintic used to treat parasitic infections in animals. The addition of an epoxy group introduces a unique structural modification that may alter its pharmacological properties. Moxidectin functions by binding to glutamate-gated chloride channels in parasites, leading to paralysis and death. Research on 3,4-Epoxy-moxidectin may focus on its effects on parasite physiology, interactions with ion channels, and potential applications in veterinary medicine.