3,N4-Etheno-2’-deoxycytidine

• CAT Number: C000654
• CAS Number: 68498-26-0
• Molecular Formula: C₁₁H₁₃N₃O₄
• Molecular Weight: 251.24
• Purity: ≥95%
• Synonyms: 3,N4-Etheno-dC; 3,N4-Ethenodeoxycytidine; Ethenodeoxycytidine; 6-(2-Deoxy-β-D-erythro-pentofuranosyl)imidazo[1,2-c]pyrimidin-5(6H)-one
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• Appearance: White to Off-White Solid
• Storage: 4°C
• IUPAC Name: 6-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazo[1,2-c]pyrimidin-5-one
• InChI: InChI=1S/C11H13N3O4/c15-6-8-7(16)5-10(18-8)14-3-1-9-12-2-4-13(9)11(14)17/h1-4,7-8,10,15-16H,5-6H2/t7-,8+,10+/m0/s1
• InChIKey: UFLBVEMEAYZXKY-QXFUBDJGSA-N
• SMILES: C1C(C(OC1N2C=CC3=NC=CN3C2=O)CO)O

3, N4-Etheno-2’-deoxycytidine (Cat No.:C000654) is a modified nucleoside derivative that contains an ethanol bridge between the third and fourth positions of the cytosine ring. This modification results in a distorted DNA structure that can affect DNA replication and repair processes. Research on 3, N^4-Etheno-2’-deoxycytidine may focus on its impact on DNA integrity, mutagenic potential, and interactions with cellular pathways.

Reference

Shen, M., et al.: Sci. Total Environ., 543, 267-273 (2016); Li, H., et al.: Free Radical Res., 49, 1049-1054 (2015); Cui, S., et al.: Int. J. Environ. Res. Public Health, 11, 10902-10914 (2014)