(3R,8S)-Falcarindiol

• CAT Number: R051725
• CAS Number: 225110-25-8
• Molecular Formula: C17H24O2
• Molecular Weight: 260.37
• Purity: ≥95%
• Synonyms: (3R,8S,9Z)-1,9-Heptadecadiene-4,6-diyne-3,8-diol; (+)-(3R,8S)-Falcarindiol; (3R),(8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: (3R,8S,9Z)-heptadeca-1,9-dien-4,6-diyne-3,8-diol
• InChI: InChI=1S/C17H24O2/c1-3-5-6-7-8-9-10-14-17(19)15-12-11-13-16(18)4-2/h4,10,14,16-19H,2-3,5-9H2,1H3/b14-10-/t16-,17+/m1/s1
• InChIKey: QWCNQXNAFCBLLV-YWALDVPYSA-N
• SMILES: CCCCCCCC=CC(C#CC#CC(C=C)O)O

Falcarindiol（Cat No.:R051725）, also known as FAD, (3R, 8S)-Falcarindiol, or FaDOH, is a natural polyacetylene compound found in various plants of the Umbelliferae family. It exhibits inhibitory effects on the expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1beta (IL-1β) stimulated by LPS. Falcarindiol also attenuates LPS-induced activation of signaling molecules such as JNK, ERK, STAT1, and STAT3. Additionally, Falnidamol, a pyrimidine derivative, demonstrates anticancer activity. These compounds hold potential for further research and development in various therapeutic applications.