(3S,4R,5S)-rel-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid

• CAT Number: I043091
• CAS Number: 1219086-89-1
• Molecular Formula: C23H22Cl2F2N2O2
• Molecular Weight: 467.34
• Purity: ≥95%
• Synonyms: (2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carboxylic acid
• InChI: InChI=1S/C23H22Cl2F2N2O2/c1-22(2,3)10-17-23(11-28,14-8-7-12(24)9-16(14)26)18(20(29-17)21(30)31)13-5-4-6-15(25)19(13)27/h4-9,17-18,20,29H,10H2,1-3H3,(H,30,31)/t17-,18-,20+,23-/m0/s1
• InChIKey: IIEWBFYJGJATRB-DWXLDPMZSA-N
• SMILES: CC(C)(C)C[C@H]1[C@]([C@H]([C@@H](N1)C(=O)O)C2=C(C(=CC=C2)Cl)F)(C#N)C3=C(C=C(C=C3)Cl)F

(3S,4R,5S)-rel-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid（Cat No.:I043091）is a highly functionalized pyrrolidine derivative used in pharmaceutical research and drug discovery. The presence of chloro and fluorophenyl groups enhances lipophilicity and metabolic stability, making it a potential candidate for enzyme inhibition and receptor binding studies. Its cyano and carboxylic acid functional groups allow for further derivatization in medicinal chemistry. This compound is particularly valuable in neuropharmacology, antiviral drug design, and small-molecule therapeutic development, where structurally rigid pyrrolidine scaffolds contribute to improved bioactivity and selectivity.