4β-Hydroxywithanolide E

• CAT Number: R066358
• CAS Number: 54334-04-2
• Molecular Formula: C28H38O8
• Molecular Weight: 502.60
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: (1S,2R,6S,7R,9R,11R,12R,15S,16S)-15-[(1S)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-6,12,15-trihydroxy-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadec-4-en-3-one
• InChI: InChI=1S/C28H38O8/c1-14-12-20(35-22(31)15(14)2)25(5,32)27(34)11-10-26(33)17-13-21-28(36-21)19(30)7-6-18(29)24(28,4)16(17)8-9-23(26,27)3/h6-7,16-17,19-21,30,32-34H,8-13H2,1-5H3/t16-,17+,19-,20+,21+,23-,24-,25-,26+,27-,28+/m0/s1
• InChIKey: UPBUGICUKQIKTJ-KABTZXSUSA-N
• SMILES: CC1=C(C(=O)OC(C1)C(C)(C2(CCC3(C2(CCC4C3CC5C6(C4(C(=O)C=CC6O)C)O5)C)O)O)O)C

4β-Hydroxywithanolide E(CAT: R066358) is a naturally occurring withanolide, a class of steroidal lactones primarily found in plants of the Solanaceae family, particularly in Withania somnifera (Ashwagandha). This compound is noted for its diverse biological activities, including anti-inflammatory, anticancer, and immunomodulatory effects. 4β-Hydroxywithanolide E has been extensively studied for its potential to induce apoptosis in cancer cells, inhibit tumor growth, and modulate immune responses. It also exhibits neuroprotective properties, making it a valuable compound in neurodegenerative disease research. Its broad range of pharmacological activities makes 4β-Hydroxywithanolide E an important molecule in natural product-based drug discovery and development.