4-​(2-​Oxiranylmethoxy)​-​9-​(2-​oxiranylmethyl)​-9H-​carbazole

• CAT Number: C000300
• CAS Number: 1198090-71-9
• Molecular Formula: C₁₈H₁₇NO₃
• Molecular Weight: 295.33
• Purity: ≥95%
• Synonyms: 4-(Oxiran-2-ylmethoxy)-9-(oxiran-2-ylmethyl)-9H-carbazole
• Solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
• Appearance: Off-White to Pale Orange Solid
• Storage: -20°C, Inert atmosphere

4-(2-Oxiranylmethoxy)-9-(2-oxiranylmethyl)-9H-carbazole(CAT: C000300) serves as a crucial intermediate in the synthesis of N-2-Hydroxy-3-[[2-(methoxyphenoxy)ethyl]amine Carvedilol (Carvedilol EP Impurity A). This compound plays a pivotal role in the pharmaceutical industry, particularly in the production of carvedilol and its associated impurities. Careful control and analysis of intermediates like this are essential in pharmaceutical manufacturing to ensure the quality, purity, and safety of the final drug product.

Reference

Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996)